Precursor of Glutathione. Toghether with Selenium, it makes up the glutathione peroxidase enzyme, a powerful intracellular antioxidant, which also exert an important chelating action for toxic metals.
NAC acts through two mechanisms:
• Intracellular “scavenger” of free radicals toghether with a slowdown of cellular apoptosis.
• Vasodilatator action, because of the association with nitric oxide causing an improvement of cerebral and peripheral function. One of the most important preventive action in case of Alzheimer and Parkinson’s deseases and atherosclerosis and cerebral ischemia is fighting the oxidative stress affecting the brain.

Selenium is an essential trace element for the glutathione peroxidase enzyme. It protects cells from environmental damage and pollution. It takes part in the metabolism of thyroid hormones ( in particular TSH and T3. Their concentration diminishes during degenerative-cognitive or post-micro-schemic processes).
Various studies have showen that a Selenium deficit speeds up cognitive impairment, whereas supplementing Selenium improves the brain function in predisposed subjects.

Manfanese is an essential mineral which carries out an antioxidant action. It plays an important role in the superoxide dismutase (SOD) enzymatic system. Moreover, it is essential for brain activity both in the control of neurotransmitters and in the neuron use of glucose. A correct balance of the central nervous system depend on a good level of Manganese. A Manganese deficit reduces the dopamine levels.

It protects tissues and cells from hypoxia which occurs due to aging and cerebral ischemia.
Q10 synthesis begin to decrease gradually from 35-40 years of age: even different chronic pathologies and a long-term use of synthetic drugs (such as statins) can negatively influence Coenzyme Q10 syntesis.

This plant is considered as one of the most powerful natural adaptogens; the biological and pharmaceutical effects of the root phytocomplex mus be ascribrf to “whitanolides”,i.e.,steroidal molecules with a variety of pharmacological properties that help:
• improve neuronal trophism to regenerate axon and dendritic endings
• protect the hippocampal structures,i.e.,the seats of memory
• modulate the acetylcholinesterase enzyme involving an increase of the synaptic impulse.

The green tea (Camellia sinensis) extract contained in Gunabrain is particulary rich in tannis, alkaloids, saponins, vitamins, minerals and trace elements carrying out:
• an antioxidant action
• an anti-inflammatory action
• an hypocholesterolemic action
• a support action to the cardio circulatory function.